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Services
The toxicology department carries out the following types of the studies
 Acute studies - oral, dermal, inhalation, skin and eye irritation / sensitization.
Sub-acute / Sub chronic studies - oral, dermal and inhalation.
Chronic studies
Segment I, II & III studies for pharmaceuticals
Carcinogeneicity 1, 2, 3 - Generation reproduction, Teratology, studies.
Genotoxicity studies.
Neurotoxicity.
Ecotox studies using birds, fish, algae, earthworm, daphnia, honey bees, etc.
Metabolism.
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The following test species are available at our facility for conducting the studies
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Wistar rats |
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Swiss albino mice |
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New Zealand white rabbits |
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Guinea pigs -Duncan Harley |
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Chicken |
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Pigeon |
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Quail Japanese/German |
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Fresh water fish (Carp/Zebra/Guppies) |
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Indian and European Honeybees |
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Algae and Daphnia |
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Earthworms |
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Honey bees |
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Residue / Analytical |
The residue analytical lab at the RRC, supporting toxicology work, is equipped with state-of-the-art analytical instruments like GLC, HPLC, GC/MS, NMR, IR, AAS and V-visible spectrophotometer.
In addition to supporting toxicological studies, the analytical services include : Physical and Chemical properties and Five batch analysis as per USEPA (OPPTS) / OECD / SETAC Guidelines and EEC / CIPAC methods.
Studies on persistence, residue and environmental fate of pesticides are carried out for evaluation of their consumer and environmental safety in compliance with Good Agricultural Practice (GAP) and Good Laboratory Practice (GLP). Pesticide residues and their metabolites are analysed in diverse substrates, viz., soil, water, air, plants, animal feeds and tissues.
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